Back to nutrition and energy

Research summary · Nutrition and energy

Supplements and lower-limb power: signals with uneven certainty

A large network review compares dietary supplements across four separate lower-limb power and jump outcomes.

Publication year
2026
First published online
Publication type
Systematic review and Bayesian network meta-analysis
Journal
Journal of the International Society of Sports Nutrition
Population / context
Physically active people and athletes · Power and jump tests

What the publication reports

The review included 119 randomised parallel or crossover studies. HMB showed favourable estimates for peak and relative peak power; several other supplements showed outcome-specific signals, including betaine for countermovement jump and iron for vertical jump, although the iron estimate came from one direct study.

Limits and interpretation

Of 1,636 pairwise comparisons, 1,564 were graded very low certainty and only 17 moderate. Sparse networks, imbalanced covariates and sensitivity analyses that attenuated some findings mean rankings should not guide an individual supplement regimen.

Original editorial summary by iintroo editorial · Added · Source-checked .

This is an educational research summary, not a reproduced abstract, a new scientific study or an individual treatment plan.

Reader discussion

Discuss the evidence.

Moderated comments

Ask a question, share a source or discuss the methods. Respectful disagreement is welcome. Every comment and reply is reviewed before publication.

No profanity, harassment, hate, threats, spam or identifiable patient details. Discussion rules and privacy

Loading comments…