Source-checked report · National
Lions beat Cardinals 45-21 with 38 points across middle quarters
Detroit scored 24 points in the second quarter and 14 in the third on the way to a 45-21 road win.
Detroit Lions defeated Arizona Cardinals 45-21 on 11 October 2026 in a completed NFL Week 5 game at State Farm Stadium. The NFL game center records the final status and score.
Detroit trailed 7-0 after the first quarter, then outscored Arizona 38-7 across the second and third periods before both teams added seven in the fourth.
The result is treated as one completed game development. Quarters, turnovers and individual player performances are not split into filler reports.
The NFL game record and Week 5 review establish the official outcome, while an independent report corroborates the result. The story was checked against every archive and current collection, calendar data, the live posts table and the durable publication log.
Sources
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